宫颈癌机会性筛查的应用与分析.doc

宫颈癌机会性筛查的应用与分析

【摘要】论文目的:探讨宫颈癌机会性筛查的应用及意义。论文方法:为2008年1月~12月在新疆自治区人民医院妇产科门诊就诊的患者行机会性筛查,以液基细胞学、HPV检测和阴道镜为筛查方法,活检组织病理学诊断为最终诊断标准,评价机会性筛查用于宫颈癌早诊、早治的意义。结果:4485例患者中一半以上患者不了解宫颈癌相关知识;患者筛查顺应性为98. 79% (4431/4485),检出细胞学阳性569例,阳性检出率12. 68% (569/4485); 561例行高危HPV检测,感染率36. 54% (205/561); 549例行阴道镜+活检,活检病理结果为: CINⅠ62例, CINⅡ-Ⅲ46例、SCC 8例。2008年宫颈癌筛查参与率及宫颈病变检出率与2007年同期比较差异有统计学意义(P<0. 05)。结论:通过机会性筛查相关干预措施有助于提高患者对宫颈癌的认知程度,是全面防治宫颈癌的重要内容;机会性筛查顺应性好,能够早期发现宫颈病变,是行之有效的宫颈癌筛查方法,值得推广应用。　　
【关键词】宫颈肿瘤;机会性筛查;液基细胞学检查;人乳头瘤病毒　　

The application and significance of opportunistic screening for cervical cancer
【Abstract】　Objective:To discuss the application and significance of opportunisticscreening for cervical cancer.M ethods:Patientswhowere visiting in the department ofGyne-cology of the Peoples' Hospital ofXinjiangwere performed with opportunistic screening-relatedinterventions. Screeningmethod included Thinprep CytologyTes,tHPV testing and colposcopy.The final pathological diagnosis of cervical biopsy was as the diagnostic criteria to assess themeaning of the opportunistic screening for cervical cancer at early diagnosis.Results:Among4485 cases, a halfof the patients didnt' know the knowledge of cervical cancer; screening com-pliancewas 98. 79%.AbnormalTCT results rate was 12. 68% (569/4485).The infection rateofHR-HPV was36. 54% (205/561).Biopsy resultswere as follows:CINⅠ62 cases,CINⅡ~Ⅲ46 cases, SCC 8 cases.There was statistical difference(P<0. 05)between 2008 and 2007two years in cervical lesionsdetection rate.Conclusion:In screening, to raise the cognition lev-el of cervical cancer is important for comprehensive prevention and control of cervical cancer.The opportunistic screening for cervical cancer is effective and economica.l Itcan recognize cer-vical lesions earlywith high screening compliance.　　
【Keywords】Cervix neoplasms;Opportunistic screening;Thinprep cytology tes;tHumanpapillomavirus