脑部定量核磁共振灌注成像-------外文翻译.doc

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脑部定量核磁共振灌注成像-------外文翻译,purpose:to eva luatequantitativecerebralbloodflow (qcbf) with traditional time-based measurements or metrics of cerebral perfusion: time to peak (tmax) an...
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Purpose: To eva luate quantitative cerebral blood flow (qCBF) with traditional time-based measurements or metrics of cerebral perfusion: time to peak (Tmax) and mean

transit time (MTT) in stroke patients.

Materials and Methods: Nine ischemic stroke patients (four male, five female, 63 6 16 years old) were included in the study which was Health Insurance Portability and

Accountability Act compliant and institutional review board approved. Cerebral perfusion was quantified using the Bookend method. Mean values of qCBF, Tmax, and MTT were determined in regions of interest (ROIs). ROIs were drawn on diffusion weighted images in diffusion positive, critically ischemic (CI), in ipsilateral normal region immediately surrounding the critically ischemic region,the presumed penumbra (PP), and in contralateral diffusion negative control, presumed normal region (PN) of gray and white matter separately (GM and WM).

目的:采用传统的基于时间的脑灌注测量或度量方法,定量评估脑血流量:脑卒中病人脑血流量的达峰的时间(Tmax)和平均通过时间(MTT)。

材料和方法:经过了机构审查委员会批准并遵循医疗保险便利及责任法案,本研究纳入9名缺血性脑卒中病人(4名男性,5名女性,年龄为63±16)。使用书夹法对脑灌注进行定量分析。测定了感兴趣区域(ROIs)的脑血流量均值、最大峰值时间和平均通过时间。感兴趣区域包括弥散阳性区以及严重缺血区域的弥散加权成像,迅速波