aecopd的两种治疗方法药物经济学的研究.doc
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aecopd的两种治疗方法药物经济学的研究,aecopd的两种治疗方法药物经济学的研究摘要:目的 研究两种治疗方法治疗慢性阻塞性肺疾病伴急性加重期(aecopd)的药物经济学效果。方法 采用回顾性研究方法,将102例aecopd患者按照治疗方法中使用的抗菌药物不同分为美洛西林舒巴坦钠组(a组)和头孢米诺钠组(b组),住院天数为7~14天,分别观察2组治疗后的疗效...
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AECOPD的两种治疗方法药物经济学的研究
摘要:目的 研究两种治疗方法治疗慢性阻塞性肺疾病伴急性加重期(AECOPD)的药物经济学效果。方法 采用回顾性研究方法,将102例AECOPD患者按照治疗方法中使用的抗菌药物不同分为美洛西林舒巴坦钠组(A组)和头孢米诺钠组(B组),住院天数为7~14天,分别观察2组治疗后的疗效和不良反应发生率并以其评估治疗的效果,然后运用药物经济学评价方法中的成本-效果分析方法、敏感度分析方法及DDDs进行分析。结果 A组和B组临床总有效率分别为93.55%、95.00%(P>0.05),不良反应发生率分别为3.23%、2.50%;平均住院时间分别为(9.19±2.17)天和(8.90±1.98)天,譆@杀痉直鹞�(7695.18±2993.02)元、(9648.49±2631.41)元,统计学分析两组有显著性差异(P0.05)。结论 治疗AECOPD,美洛西林舒巴坦钠治疗方法较头孢米诺钠治疗方法经济、有效、合理。
关键词:慢性阻塞性肺疾病伴急性加重期;治疗方法;成本-效果分析;敏感度分析;
DDDs
Abstract: Objective To research chronic obstructive pulmonary disease with acute exacerbation ( AECOPD) of two antibaccterial drug treatments of pharmacoeconomic effect. Methods by a retrospective exploration, so medical records were divided into Mezlocillin sodium/Sulbactam sodium (A)group and Cefninox sodium (B)group as different treatment methods, the length of hospital stay was 7~14 days, then observed 2 groups of adverse reaction and curative effect after treatment, and eva luated the effect of treatment with those, the last cost-effectiveness analysis(CEA),sensitivity analysis and frequency of medication DDDs were performed. Results The clinical total effective rates in group A and group B were 93.55% and 95.00%,the incidence of adverse reaction were 3.23%, 2.50%,Mean length of hospital stay were (9.19±2.17)days and (8.90±1.98)days, and the total costs were (7695.18±2993.02) Yuan and (9648.49±2631.41)Yuan, statistical analysis of the two groups had significant difference (P<0.05);The cost-effectiveness ratio of Mezlocillin sodium/Sulbactam sodium (A)group is lower than that of Cefninox (B)group, the sensitivity analysis results are consistent with results of parameter change.In addition, DDDsA
Keywords:AECOPD; Methods of treatment; Cost-effectiveness analysis ; Sensitivity analysis ;DDDs
摘要:目的 研究两种治疗方法治疗慢性阻塞性肺疾病伴急性加重期(AECOPD)的药物经济学效果。方法 采用回顾性研究方法,将102例AECOPD患者按照治疗方法中使用的抗菌药物不同分为美洛西林舒巴坦钠组(A组)和头孢米诺钠组(B组),住院天数为7~14天,分别观察2组治疗后的疗效和不良反应发生率并以其评估治疗的效果,然后运用药物经济学评价方法中的成本-效果分析方法、敏感度分析方法及DDDs进行分析。结果 A组和B组临床总有效率分别为93.55%、95.00%(P>0.05),不良反应发生率分别为3.23%、2.50%;平均住院时间分别为(9.19±2.17)天和(8.90±1.98)天,譆@杀痉直鹞�(7695.18±2993.02)元、(9648.49±2631.41)元,统计学分析两组有显著性差异(P0.05)。结论 治疗AECOPD,美洛西林舒巴坦钠治疗方法较头孢米诺钠治疗方法经济、有效、合理。
关键词:慢性阻塞性肺疾病伴急性加重期;治疗方法;成本-效果分析;敏感度分析;
DDDs
Abstract: Objective To research chronic obstructive pulmonary disease with acute exacerbation ( AECOPD) of two antibaccterial drug treatments of pharmacoeconomic effect. Methods by a retrospective exploration, so medical records were divided into Mezlocillin sodium/Sulbactam sodium (A)group and Cefninox sodium (B)group as different treatment methods, the length of hospital stay was 7~14 days, then observed 2 groups of adverse reaction and curative effect after treatment, and eva luated the effect of treatment with those, the last cost-effectiveness analysis(CEA),sensitivity analysis and frequency of medication DDDs were performed. Results The clinical total effective rates in group A and group B were 93.55% and 95.00%,the incidence of adverse reaction were 3.23%, 2.50%,Mean length of hospital stay were (9.19±2.17)days and (8.90±1.98)days, and the total costs were (7695.18±2993.02) Yuan and (9648.49±2631.41)Yuan, statistical analysis of the two groups had significant difference (P<0.05);The cost-effectiveness ratio of Mezlocillin sodium/Sulbactam sodium (A)group is lower than that of Cefninox (B)group, the sensitivity analysis results are consistent with results of parameter change.In addition, DDDsA
Keywords:AECOPD; Methods of treatment; Cost-effectiveness analysis ; Sensitivity analysis ;DDDs